|
How does one
choose which
CELLS
to STUDY
?
Though cells have different anatomical structure their molecules are remarkably similar thus studying cells in one organism has direct application to other organisms...
›
Model
Organisms* cheap,
plentiful, prolific reproducers, with
simple genomes
& any unique properties for practical research analysis: [see pg 27 -36]* Many of CMB's model organisms have often been used to study gene expression:
Bacteriophages
- viruses
that infect bacteria;
today many are used as
cloning vectors
Escherichia coli - a bacteria common to the Human colon ; also a molecular workhorse
Eukaryotic
models include:
plants - Arabidopsis thaliana - pic - small genome; light sensing molecular biology nematode - Caenorhabditis elegans - pic - 3 day life cycle and only 1,000 cells animals - Drosophilia melangaster - pic - fruit fly Zebrafish development* - pic - 70% of their genes are similar to Human genes Mus musculus - common house mouse & its genome-barcode* cell mapping* Cells grown in the lab - model systems for genetic & embryonic development research... Hela cells* - an immortal cell line of human cervical cancer cells filopodia that grew prolifically in culture (George & Margaret Gey at JHU) fibroblast cells - cultured connective tissue cells that produce extra cell matrix & collagen. |
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