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- Cell and Molecular
Biology
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is the study of
life & the living cell
thru an analysis of the
constituent
molecules found
within cells.
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"Life..
is a relationship between molecules."
Linus Pauling...his biography
(1997 - p.542)
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CMB is
designed to construe the
properties
of the organism
by understanding the
structure and functions of
its
constituent molecules
in
cells and their complex interactions.
How does
rhodopsin's shape contribute to human vision?
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bottom left to go to next page
CMB encompasses
the
5 BIG Ideas of Biology...
1. EVOLUTION:
organisms and their cellular & molecular
components
have changed over time through selective
evolutionary processes.
2. STRUCTURE
& FUNCTION:
living things are made of molecules,
whose spatial arrangement determines the function
of systems.
3. TRANSFORMATION
of ENERGY AND MATTER:
all living things acquire, use, and
release matter and energy for
cellular functions.
4. INFORMATION
FLOW & STORAGE:
DNA and signal molecules
are exchanged and used among cells and
organisms to direct
their functioning.
5. SYSTEMS:
Living things and their parts
are interconnected and
interact
to influence each other on many
levels of complexity.
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- Cell &
Molecular Biology
is a vibrant
&
exciting
discipline.
Today, CMB is built upon
disciplines as biochemistry and physiology,
but draws from disciplines as neurobiology,
immunobiology, microbiology,
molecular genetics,
and
developmental
biology.
Today, the term “molecular biology”
has a different meaning than it did
75 years
ago, when little was molecular.
Today, there
is little in contemporary biology
that isn't molecular.
CMB tries
to connect molecules not just to
reactions of
high specificity, but to intricate
pathways concerned with cellular,
tissue, and
organism homeostasis.
But, CMB
must move beyond binding and
catalysis to
encompass cellular morphogenesis,
development, and physiology.
cell & molecular biology is a
domain where biology, computer
science, logic,
chemistry, quantum physics, and
nanotechnology intersect, and it
also provides
a natural connection between
basic biological research and
modern medicine.
 * a text
description of CMB
(starred
links are required
reading) |
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Procedures for Mallery's Class presentations and lectures:
► The Web based
Power Point-like material is designed for
students to meet their own
unique learning
regiment. The web
site presents "baseline-needed-material "
which we all must learn, including starred*links,
that are designed to enhance
directed learning and
explain in greater detail a presented concept.
if
a web link is starred*, then you are responsible for the content at that
main link;
if a figure is listed fig
3-30 or
figure* then you're responsible for its content
also...
* text
description of Cell Biology  * Thought Questions
► Additionally, there are many
immersion-learning
links that are not starred,
about
Cell
& Molecular & topics, which allow a learner
(you) to delve into an
area of self-interest and build your
knowledge base and biology productivity.
► if a
web-link is NOT starred, then you
NOT responsible for its content on tests.
* <-- always
click on icon at lower left of webpages to go to
next page
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Some Fundamental Questions Asked via CMB ? |
what is a definition of
Life ?
how do the
properties of molecules contribute to
Life ?
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Since Life is
manifest in the
CELL... these
questions become... |
where did the
molecules of cells
(& Life)
come from
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what is the origins
of cells ?
The Origin of
Cellular Life on Earth
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what are the propertires
of cells ? |
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how does an
organism develop from single fertilized
egg ? |
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with similar
molecules what causes a great
diversity of cells & life ? |
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how do cells
work
- why do we get sick, grow old, die ? |
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| Some Course
Goals - |
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1. examine
the details of the cell, stressing
the fundamentals,
& relationships between molecules and structure & function |
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2. generate
an appreciation for how the
properties
of molecules lead to the living condition |
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3. Observe
some of the techniques
& tools
of CMB
► "Although concepts and ideas occupy a central place in
the grand sweep
of our understanding of the nature of the
world around us, it is a mistake
to imagine ideas play a greater role
than tools and techniques in achieving
scientific progress in cell &
molecular biology.
Few scientific
revolutions are concept driven." [re:
HGP].... John M. Thomas, 1994. |
4.
Recognize the integration of molecular
systems to the creation of cellular
function,
enzymatic pathways, signal molecules,
and information flow.
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5.
write down your own goals for our course.
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Faculty... |
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Daniel DiResta,
- Cox Science Bldg.,
room 166A - Senior Lecturer.
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Charles
Mallery,
- Merrick Bldg. room
304 - Associate Dean, College of Arts
and Sciences.
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Office Hours - please call their office's
for an appointment :
Mallery 284-3188 or
DiResta
284-1715 |
Textbook (spring 2020) - "Essential
Cell Biology
" 5th edition
by Alberts
et al, (ISBN 9780393679533-hardcover). |
Prerequisites - Biology 150 and 160; a
background in genetics (Bil 250)
& organic (CHM 201) is
recommended. |
Lecture -
fall-
3:30pm to 4:45pm - Tuesday & Thursday.
- spring- 2:40pm to 3:55pm -
Tuesday & Thursday & 5:00pm
Monday's.
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E-mail -
Dr. Mallery: cmallery@miami.edu
&
- Dr. DiResta: diresta@miami.edu
Bil 255 Description page by.....
Charles
Mallery, Department of Biology, College of
Arts & Sciences
University of Miami, Coral Gables, FL 33146
Copyright and Disclaimer© 2022
Thanks
to Casey B., A. Thyssen & R. Ralph for their
web icons.
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