SHOTGUN APPROACH

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sequence machines
 
  http://www.illumina.com/
         samples as small as 100ng
         with gigabases of data in a 4 hour run.

                    
Illumina Sequenceing machines


The NextSeq 2000 will have a maximum sequencing
data output of 300 Gb and a US list price of $335,000
while the NextSeq 1000 will have a maximum output
of 120 Gb and a US list price of $210,000.