| SIGNAL SEQUENCES of AUTONOMOUS ORGANELLES | ||
| ORGANELLE |
SIGNAL... TO |
Description |
| MITOCHONDRIA | mitoplasm | a mitoplasmic-targeting signal sequence in proteins that is a short sequence @ N-terminal with + charged aa's (LYS & ARG). Signal sequence folds into a-helix with +'s on one side of helix |
| outer membrane | a mitoplasmic-targeting sequence, followed by a stop transfer sequence that prevent entry through outer membrane porin channel | |
| Inter-membrane space | a mitoplasmic-targeting sequence, followed by a clevage site that results in release of protein into peri-mitochondrial space | |
| Inner-membrane space | a mitoplasmic-targeting sequence, with one of more transmembrane aa domain regions | |
| CHLOROPLAST | Chloroplasm |
contains - an
uncharged a-helix with polar aa's along one side |
| Outer membrane | may be a chloroplasm-targeting aa signal sequence and a stop transfer sequence ??? | |
| Inter-membrane space | may be a chloroplasm-targeting aa signal sequence and a clevage site that releases protein into peri-chloroplast space ??? © | |